DNA Motif

DNA Logo A DNA motif is a sequence frequency description for a particular region of DNA that appears frequently, either across species (sequence comparison) or for particular binding sites (as in [[ChiPSeq]]).

Motifs can be used to identify relationships between different proteins or Transcription Factors that bind to DNA.

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  • ChIP-seq

    One of the goals of ChIP-seq analysis is to find a unique DNA Motif associated with each protein binding site. It is assumed that a Transcription Factor binds to a semi-unique sequence on the genome. By identification of the unique motif, one can associate the bound transcription factor to the unique motif.