PU1 meeting<2025-10-27 Mon>

Part C

  • Restrict this to only DNA binding TFs (1639)

Figure 2

DONE Part D

How should I sort the GO terms? By number of significant conditions then P value?

  • Yes, sort like this, but with shared at the top, every set moved to left
  • Bigger circles

Figure 3

DONE Part A

Where does the HOMERTFdictionaryproper.txt come from?

  • Doesn't matter (this is just manual annotation)

Figure 4

  • Only the ones that end in count (do a text search)
  • No dendrograms
  • Lupus should just be lupus (remove underscores)
  • remove long disease

Figure 5

  • Scatter plot between PU.1 MARIO ARSGLOBAL and bQTL/AlphaGenome/SNPmoods
    • Ask Andrew/Xiaoting for:
      • Only PU.1 bound heterozygotes (hets)
      • All Mario Hets where there were at least 7 reads
      • UID/index, SNP ID (RSID), ARSGLOBAL, DATASET, SNPmoods, bQTL (from bulyk lab's paper), ALphaGENOME (Andrew), Number of total Reads PU.1 to that SNP
    • Density scatter plot/heatmap?
    • Flow cytometry density plot is a good example