PU1 meeting 3

T cell is expressed early in T cell development

  • There is an X over T cells currently
  • In the legend, we should point out that PU.1 is expressed in T cell development, but not in adults

DONE UMAP

  • Note taken on [2025-06-02 Mon 19:18]
    moved to the agenda
  • Set colors to match cell types figure

Add Bullets that tell you what you learn

  • Bullet summaries for each figure

GREAT ANALYSIS

  • Start with Biological process (GREAT)
  • 7 or 8 (eosinophil) (lump together)
  • GO slim (removes redundant pathways)
  • Lee has the code

DONE Figure 3

  • Note taken on [2025-06-02 Mon 19:17]
    Moved to the agenda

Reorder columns by ets, spi1, content

DONE MARIO, Phenotype RELI

  • Note taken on [2025-06-02 Mon 19:18]
    moved to agenda
  • Connect to GWAS (Leah sent out new catalogue)
  • write resuable tool for this plot

Phenotype RELI

A clustered heatmap (rows are diseases, columns are cell types)

Harley et al. 2018 Last figure?

  • New disease RELI
  • Over half of "diseases" are measurements (blood pressure) that are not necessary
  • Don't inlcude social variables
  • Run RELI before making figures