Dysregulated immune response to ebola virus
experimental design
Cell types
- CD4+
- CD8+
- Monocytes
Day 4
- RNA-seq
- ATAC-seq
- CUT&RUN
Day 6
Animals were not doing well at this point, so this was the final time step.
- RNA-seq
- ATAC-seq
- CUT&RUN
EBOV gene expression across cell types
- mock on day 4 was lost
- CD8 and Monocytes are similar
Tissue specific points
Higher expression in the kidney
ATAC
CD4 and CD8 have many more differentially available peaks.