Wet Lab meeting 2

  • Re-use before recycling

Matt Hass

HSV2 RL2-nGFP form nuclear foci, known to interact with PML body.

RL2 = ICP0 in other viruses

PML body

  • may be involved in stress response
  • known sub-nuclear complex (protein)

Shingles and Dimentia in Wales

Paper: Natural experiment on the effect of herpes zoster vaccination on dementia

  • Shingles (VZV) vaccine shows 20% decrease in dementia
  • Similar results to other groups

Leah

World's first personalized CRISPR therapy

  • Genome Editing for rare genetic diseases in the liver

Lois

  • Jurkat cells are growing nicely
  • Designed CRISPR RNAs and sent to company (CRISPIC)
  • Nextflow pipeline worked, but barcode reads have issues

Katelyn

  • vTR0326 sequencing didn't work